Ergot

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expialidocious
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Ergot

Postby expialidocious » Aug 27, 2018 6:58 am

The story of a parasitic fungus

Up to the 19th century, prior to the introduction of grain standards for ergot, the sclerotia were ground up with rye grains and consumed because most of the flour was used for baking. Chronic consumption leads to symptoms that are summarized as "ergotism".
Biology, Genetics, and Management of Ergot...

Ergotism is extremely rare today, primarily because the normal grain cleaning and milling processes remove most of the ergot so that only very low levels of alkaloids remain in the resultant flours. In addition, the alkaloids that are the causative agents of ergotism are relatively labile and are usually destroyed during baking and cooking.—Toxic effects of mycotoxins in humans

Clinical ergotism as seen today results almost exclusively from the excessive intake of ergotamine tartrate in the treatment of migraine headache.
Ergot Intoxication...

Prophylactic intramuscular or intravenous injections of ergot alkaloids are effective in reducing blood loss and postpartum haemorrhage, but adverse effects include vomiting, elevation of blood pressure and pain after birth requiring analgesia, particularly with the intravenous route of administration.
Use of ergot alkaloids in the third stage of labour

Ergot derivatives are known to induce the spasmodic contraction of coronary arteries. Administration of ergot derivatives can cause acute myocardial infarction (AMI), even in normal healthy people. In several reported cases, ergot derivatives triggered severe AMI during the postpartum period. Here, we report the case of a forty-year-old woman who was successfully impregnated by artificial fertilization and died after treatment with ergot derivatives.
An Autopsy...

The end

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BloodyHell
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Re: Ergot

Postby BloodyHell » Aug 28, 2018 3:30 pm

Bloody Hell! How can you even remotely regard this article as having anything to do with discussing a movie? -- :scratch:

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expialidocious
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Re: Ergot

Postby expialidocious » Aug 30, 2018 1:54 am

It's a documentary, you see... and I was just bringing it up to date (from 1958). It's like they said, "there are two sides to the Ergot story: on the one hand there is its value in therapeutics, on the other its poisonous nature" (even in therapeutics, apparently—they left that part out).

expialidocious wrote:The story of a parasitic fungus

Up to the 19th century, prior to the introduction of grain standards for ergot, the sclerotia were ground up with rye grains and consumed because most of the flour was used for baking. Chronic consumption leads to symptoms that are summarized as "ergotism".
Biology, Genetics, and Management of Ergot...

Ergotism is extremely rare today, primarily because the normal grain cleaning and milling processes remove most of the ergot so that only very low levels of alkaloids remain in the resultant flours. In addition, the alkaloids that are the causative agents of ergotism are relatively labile and are usually destroyed during baking and cooking.—Toxic effects of mycotoxins in humans

Clinical ergotism as seen today results almost exclusively from the excessive intake of ergotamine tartrate in the treatment of migraine headache.
Ergot Intoxication...

Prophylactic intramuscular or intravenous injections of ergot alkaloids are effective in reducing blood loss and postpartum haemorrhage, but adverse effects include vomiting, elevation of blood pressure and pain after birth requiring analgesia, particularly with the intravenous route of administration.
Use of ergot alkaloids in the third stage of labour

Ergot derivatives are known to induce the spasmodic contraction of coronary arteries. Administration of ergot derivatives can cause acute myocardial infarction (AMI), even in normal healthy people. In several reported cases, ergot derivatives triggered severe AMI during the postpartum period. Here, we report the case of a forty-year-old woman who was successfully impregnated by artificial fertilization and died after treatment with ergot derivatives.
An Autopsy...

The end

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BloodyHell
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Re: Ergot

Postby BloodyHell » Aug 30, 2018 3:55 pm

:oops:

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expialidocious
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Re: Ergot

Postby expialidocious » Aug 31, 2018 8:55 pm

It's kind of obscure. I got some rye flour and looked up nutritional info on it, then it was like, wow... now I'm trying to find out what the risk of "ergotism" is from eating it. I guess it used to be risky! By the way, there was another short film based on its hallucinogenic nature (relative toLSD :color:).


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